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This report is the result of a collaboration of leading popular movements, NGOs, activists, academics and health workers. It provides an evidence-based analysis of the political economy of health and health care and challenges policies and initiatives of global organisations including the World Bank, the World Health Organization and UNICEF. Many key issues relevant to health are covered, including health care services and systems, health of vulnerable groups, climate change, food and water, education, armed conflicts. Part E also provides and assessment of the impact global institutions, transnational corporations and rich countries. This report is a call for action, directed to health workers and activists and national and international policy-makers